Collagen Coating on Titanium Alloy (TNTZ) with Dip Coating Method as Prosthetic Devices in Biomedical Aplications

Abstract

Metallic biomaterials have been used widely for biomedical application. One of them is titanium alloy that has proved having good biocompatibility to human body. In other hand, the materials should preferably posses a low Young’s modulus in order to inhibit the stress shielding effect which would probably cause excessive bone absorption because of decreased mechanical stimulation to that part of bone replaced with metallic medical devices. One such alloy has been developed, TNTZ, is a ß-type titanium alloy and having low Young's modulus  (40–60 GPa) similar to that of bone (10–30 GPa), so it is suitable as prosthetic devices especially and other biomedical devices. However, metal is considered as foreign object that may cause negative effects. It is necessary, therefore, to do surface modified with biological materials to reduce those effect. One way is surface coating with collagen, where that is one of human body components and also in human bone. Surface coating with collagen has been done with time and temperature variations. The research method was dip coating method with 5, 15, and 25 minutes for time variations, and 40C and 270C (room temperature) for temperature variations. The result showed that the best result for surface coverage is 5 minute and 40C treatment. Surface coverage is 96% with thickness was 5.2 μm. Temperature variations did not have effect significantly for surface coverage and the thickness. We concluded that the best method to coat titanium, TNTZ surface with collagen with dip coating method is 5 minutes, 40C treatment to acquire the surface coverage orderly